Click here for a link to the pubmed record for our papers. Clicking the names at the beginning of each reference should link to a download for the pdf file of the respective article.

2014

Francia, M.E., and Striepen B. (2014) Cell division in apicomplexan parasites, Nature Reviews Microbiology, in press.

2013

Gorla, S.K., McNair, N.N., Hu, M., Jala, V.R., Haribabu, B., Striepen, B., Cuny, G.D., Mead, J.R., and Hedstrom, L. (2013) Validation of IMP dehydrogenase as a target for anticryptosporidial therapy in a mouse model of acute disease. Antimicrob. Agents Chemother., in press.

Striepen, B. (2013) Time to tackle cryptosporidiosis, Nature 503: 189-191

Bowman, J.D., Merino, E.F., Brooks, C.F., Striepen, B., Carlier, P.R., and Cassera M.B. (2013) Anti-apicoplast and gametocytocidal screening to identify the mechanism of action of compounds within the Malaria Box. Antimicrob. Agents Chemother. In press, epub ahead of print. a

Li, Z.H., Ramakrishnan, S., Striepen, B., and Moreno, S.N.(2013) Toxoplasma relies on both host and parasite isoprenoids and can be rendered sensitive to atorvastatin, PLoS Pathogens 9 e1003665.

Suvorova, E.S., Radke, J., Vinayak, S., Kratzer, S., Striepen, B., and White, M.W.(2013) A nucleolar AAA-NTPase is required for parasite division. Mol. Microbiol. 90:338-355.

Ramakrishnan, S, Serrichio, M., Striepen, B., and Bütikofer, P. (2013) Lipid Synthesis in Protozoan Parasites: a Comparison Between Kinetoplastids and Apicomplexans. Progress in Lipid Research 52: 488-512.

van Dooren, G.G. and Striepen B. (2013) The algal past and parasite present of the apicoplast. Annu Rev. Microbiol 67: 271–289.

Agrawal, S., Chung, D.W.D., van Dooren, G.G., Ponts, N., Brooks, C.F., Prudhomme, J., Rodrigues, E.M., Tan, J.C., Ferdig, M.T., and Striepen, B. Le Roch, K.G., (2013) An apicoplast localized ubiquitylation system is required for the import of nuclear-endcoded plastid proteins. PLoS Pathogens 9: e1003426. (shared senior authorship)

Gorla, S., Kavitha, M., Zhang, M., Chin, J., Liu, X., Striepen, B., Makowska-Grzyska, M., Kim, Yo., Joachimiak, A., Hedstrom, L., and Cuny, G. (2013) Optimization of benzoxazole-based inhibitors of Cryptosporidium parvum inosine 5’-monophosphate dehydrogenase. J. Med. Chem. 56: 4028-4043.

Coombes, J.L., Charsar, B.A., Han, S.J., Halkias, J., Chan, S.W., Koshy, A.A., Striepen, B., and Robey, E.A. (2013) Motile invaded neutrophils in the small intestine of Toxoplasma gondii infected mice reveal a potential mechanism for parasite spread. Proc. Natl. Acad. Sci. U.S.A.110: E1913-1922.

Cai. G., Deng, L., Xue, J., Moreno, S.N., Striepen, B. and Song, Y. (2013) Expression, Characterization and Inhibition of Toxoplasma gondii 1-Deoxy-D-xylulose-5-phosphate Reductoisomerase. Bioorganic & Medicinal Chemistry Letters 23: 2158-2161.

Johnson, C.R., Gorla, S.K, Kavitha, M., Zhang, M. Liu, X., Striepen, B., Mead, J.D., Cuny, G.D., and Hedstrom, L. (2013) Phthalazinone Inhibitors of Inosine-5’-Monophosphate Dehydrogenase from Cryptosporidium parvum. Bioorganic & Medicinal Chemistry Letters 23: 1004-1007.

2012

Francia, M.E., Jordan, C.N., Patel, J., Sheiner, L., Demerely, J.L., Fellows, J.D., deLeon, J., Morrissette, N.S., Dubremetz, J.F., and Striepen, B.(2012) Cell division in apicomplexan parasites is organized by a homolog of the striated rootlet fiber of algal flagella. PLoS Biology,10:e1001444. (cover)

MacRae, J.I, Sheiner, L, Naid, A., Tonkin, C., Striepen, B., and McConville, M.J. (2012) A GABA shunt and TCA cycle have important roles in the energy metabolism of intra- and extracellular Toxoplasma gondii stages. Cell Host & Microbe. 12: 682-692 (joint first and senior authors)

Glaser, S., van Dooren, G.G., Agrawal, S., Brooks, C.F., McFadden, G.I., Striepen, B., and Higgins, M.K. (2012) Tic22 is an essential chaperone required for protein import into the apicoplast. J. Biol. Chem. 287: 39505-39512

Gorla, S.K, Kavitha, M., Zhang, M. Liu, X., Sharling, L., Gollapalli, D.R., Striepen, B., Cuny, G.D. and Hedstrom, L.(2012) Selective and potent urea inhibitors of Cryptosporidium parvum inosine 5’-monophosphate dehydrogenase. J. Med. Chem. In press.

Reiff, S.B., Vaishnava, S., and Striepen B.(2012) The HU protein is important for apicoplast genome maintenance and inheritance in Toxoplasma gondii. Euk. Cell 11: 905-915.

Sheiner, L. and Striepen, B.(2012) Protein sorting in complex plastids Biochim Biophys Acta., in press.

Sampels V, Hartmann A, Dietrich I, Coppens I, Sheiner L, Striepen B, Herrmann A, Lucius R, Gupta N. (2012) Conditional mutagenesis of a novel choline kinase demonstrates the plasticity of phosphatidylcholine biogenesis and gene expression in Toxoplasma gondii. J. Biol. Chem. 287:16289-99.

Kirubakaran S., Gorla S.K., Sharling L., Zhang M., Liu X., Ray S.S., Macpherson I.S., Striepen B., Hedstrom L., Cuny G.D. (2012) Structure-activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH. Bioorg Med Chem Lett. 22(5):1985-8

Ramarkrishnan, S., Docampo, M.D., Macrae, J.I., Pujol, F., Brooks, C.F., van Dooren, G.G., Hiltunen, J.K., Kastaniatos, A, McConville, M.J., and Striepen, B. (2012) The apicoplast and endoplasmic reticulum cooperate in fatty acid biosynthesis in the apicomplexan parasite Toxoplasma gondii, J. Biol. Chem., 287: 4957-4971.

2011

Besteiro, S., Brooks, C.F., Striepen, B., and Dubremetz, J.F. (2011) Autophagy protein Atg3 is essential for maintaining mitochondrial integrity and for normal intracellular development of Toxoplasma gondii tachyzoites. PLoS Pathogens, 7: e1002416.

Sheiner, L., Demerely, J., Poulson, S., Michael Benke, White, Michael and Striepen, B. (2011) A systematic screen to discovery and analyze apicoplast proteins identifies a conserved and essential protein import factor. PLoS Pathogens, 7: e1002392.

Striepen, B. (2011) The apicoplast: a red alga in human parasites. Essays in Biochem. 24:111-25. 7.

Nair, S.C. and Striepen, B. (2011) What do human parasites do with a chloroplast anyway?. PLoS Biology 9: e1001137.

Nair, S.C., Brooks, C.F., Goodman, C.D, Sturm, A., McFadden,G.I., Sndriyal, S., Anglin, J.L, Song, Y., Moreno, N.J., and Striepen, B. (2011) Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance in Toxoplasma. J. Exp. Med. 208: 1547-1559.

Brooks, C.F., Francia, M.E., Gissot, M. Croken, M.M., Kim, K., and Striepen, B. (2011) Toxoplasma gondii sequesters centromeres to a specific nuclear region throughout the cell cycle. Proc. Natl. Acad. Sci. 108: 3767-3772.

2010

Agrawal, S. and Striepen, B. (2010) More membranes more proteins: protein import into complex plastids. Protist. 161(5):672-87.

Lorestani, A.,  Sheiner, L., Yang, K., Robertson, S, Sahoo,  N., Brooks, C.F., Ferguson, D., Striepen, B., and Gubbels, M.-J. (2010) A Toxoplasma MORN1 null mutant is defective in basal complex assembly and apicoplast division. PLoS ONE 19: e12302.

Gorla, S.K., Johnson, C., Khan, J., Sun,  X., Sharling, L., Striepen, B. and Hedstrom, L. (2010) Targeting prokaryotic enzymes in the eukaryotic pathogen Cryptosporidium. In Becker, K. (Ed.) Drug Development for Apicomplexan Parasites pp: 271-285.

Sharling, L., Liu, X., Gollapalli D.R., Maurya S. K. Hedstrom, L., Striepen, B. (2010) A screening pipeline for antiparasitic agents targeting Cryptosporidium inosine monophosphate dehydrogenase. PLoS Negl. Trop. Dis., 4(8):e794

Sun, X., Sharling, L., Mudeppa, D.G., Pankiewicz, K., Rathod, P.K., Mead, J., Striepen, B., and Hedstrom, L. (2010) Prodrug activation by Cryptosporidium Thymidine Kinase. J. Biol. Chem, 285:15916-15922.

Agrawal, S., Nair, S., Sheiner, L., and Striepen, B. (2010) The apicoplast: an ancient algal endosymbiont in Apicomplexa. In De Souza, W. (Ed.) Structures and organelles in parasitic protozo. Microbiology Monographs. Springer, pp 253-283.

Brooks, C.F., Johnsen, H., van Dooren, G.G., Muthalagi, Liu, S.S., M, Bohne, W., Fischer, K., and Striepen, B. (2010) The phosphate translocator is the source of carbon and energy for the Toxoplasma apicoplast and essential for parasite survival. Cell Host & Microbe 7: 62-73

2009

Agrawal S, van Dooren GG, Beatty WL, Striepen B. (2009) Genetic evidence that an endosymbiont-derived ERAD system functions in import of apicoplast proteins. J. Biol. Chem. 284: 33683-33691.

Chtanova, T., Han, S.J., Schaeffer, M., van Dooren, G.G., Herzmark, P., Striepen, B., and Robey, E.A. (2009) Dynamics of T cell, antigen presenting cell, and pathogen interactions during recall responses in the lymph node. Immunity 31:342-55.

Reiff, S.B. and Striepen B. (2009) Malaria: The gatekeeper revealed. Nature 459: 918-919.

Schaeffer, M., Han, S.J., Chtanova, T., van Dooren, G.G., Herzmark, P., Striepen, B*, and Robey, E.A.(2008) Dynamic imaging of T cell – parasite interactions in the brains of mice chronically infected with Toxoplasma gondii. J. Immunol182: 6379-6393.

Breinich, M.S., Ferguson, D.J.P, Foth, B.J., van Dooren, G.G., Lebrun, M., Quon, D.V., Striepen, B., Bradley, P.J., Frischknecht, F., Carruthers, V.B., and Meissner, M. (2009) A dynamin is required for the biogenesis of secretory organelles in Toxoplasma gondii. Current Biology 19: 277-286.

van Dooren, G.G., Reiff, S, Tomova, C., Meissner, M., S., Humbel, B., M., and Striepen, B. (2009) A novel dynamin-related protein has been recruited for apicoplast fission in Toxoplasma gondii. Current Biology 19: 267-276.

Striepen, B (2009) Drug Resistance and Emerging Targets in the Opportunistic Pathogens Toxoplasma gondii and Cryptosporidium parvum. in D.L. Mayers (ed.), Antimicrobial Drug Resistance, Humana Press. pp 506-619.

2008

van Dooren, G.G., Tomova, C., Agrawal, S., Humbel, B. , M., and Striepen, B. (2008) Toxoplasma gondii Tic20 is essential for apicoplast protein import. Proc. Natl. Acad. Sci. 105:13574-13579.

Chtanova, T. , Schaeffer, M., Han, S.J., van Dooren, G.G., Striepen, B., Nollmann, M., Herzmark, P., Chan, S.W., Satija, H., Camfield, K., Aaron, H., Striepen, B., and Robey E.A. (2008) Dynamics of neutrophils in lymph nodes during infection Immunity 29: 1-10.

Denkers, E.Y. and Striepen, B. (2008) Deploying parasite profilin on a mission of invasion and danger. Cell Host & Microbe 3, 61-63.

Gubbels, M.J., Lehmann, M., Muthalagi, M., Jerome, M.E., Brooks, C., Szatanek, T. Flynn, J., Parrot, B., Radke, J., Striepen, B. * and  White, M.W. * (2008) Forward genetic analysis of the apicomplexan cell division cycle in Toxoplasma gondii. PLoS Pathogens 4: E36. (*joint senior authors, first author from Striepen lab)

Umejiego, N.N., Gollapalli, D., Sharling, L., Volftsun, A., Lu, J., Stroupe, A.H.,Benjamin, N., Striepen, B. and Hedstrom, L. (2008) Targeting a prokaryotic protein in a eukaryotic pathogen: identification of lead compounds against Cryptosporidiosis. Chemistry & Biology 15: 70-77. (Editor’s choice Science 319: 870).

2007

Striepen, B. (2007) Switching Parasite Proteins on and off. Nature Methods 4:999-1000.      

Mazumdar, J. and Striepen, B. (2007) Make it or take it – the fatty acid metabolism of apicomplexan parasites. Eukaryot. Cell 6: 1727-35.

Striepen, B., Jordan, CN, Reiff, S., and van Dooren, G. (2007) Building the perfect parasite: apicomplexan cell division, PLoS Pathogens 3: e78.       

Gubbels, M.J., Mazumdar, J., van Dooren, G., and Striepen, B. (2007) Manipulating the Toxoplasma genome, in Ajioka, J. and Soldati, D., Toxoplasma biology, Humana Press, pp 239-260

Striepen, B. and Sodati, D. (2007) Genetic manipulation of Toxoplasma gondii. In: Toxoplasma gondii the Model Apicomplexan - Perspective and Methods. Weiss, L.D. and Kim, K. (Eds.) Elsevier. pp 391-415.

2006

Vaishnava, S. and Striepen, B., (2006) The cell biology of endosymbiosis - how parasites build, divide and segregate the apicoplast, Mol. Microbiol. 61: 1380–1387

Mazumdar, J., Wilson, E., Masek, K. Hunter, C., and Striepen, B. (2006) Apicoplast fatty acid synthesis is essential for organelle biogenesis and parasite survival in Toxoplasma gondii. Proc. Natl. Acad. Sci, 103: 13192–13197.

Andrade, R.M., Wessendarp, M, Gubbels, M.J., Striepen, B., and Subauste, C.S. (2006) CD-40 incuces macrophage anti-microbial activity by triggering authophagy-dependent fusion of pathogen-containing vacuoles and lysosomes. J. Clin. Invest. 116: 2366-77.

Striepen, B. (2006) Drug resistance and emerging targets in the opportunistic pathogens Toxoplasma gondii and Cryptosporidium parvum, Mayers, D., Lerner, S., Ouellette, M and Sobel, J. (Eds.) Antimicrobial Drug Resistance: Principles and Practice for the Clinic and Bench. Humana Press, in press.

Gaji, R.Y., Zhang. D., Breathnach, C.C., Vaishnava, S., Striepen, B., and Howe, D.K. (2006) Molecular genetic transfection of the coccidian parasite Sarcocystis neurona. Mol. Biochem. Parasitol. 150: 1-9.

Golanzka, J., Striepen, B., and Ullman, B. (2006) Adenosine kinase from Cryptosporidium parvum. Mol. Biochem. Parasitol. 149: 223-230.

Gubbels, M.J.,  Vaishnava, S.,  Boot, N., Dubremetz, J.F. and Striepen, B., (2006) A MORN-repeat protein is a dynamic component of the cell division machinary in Toxoplasma gondii. J. Cell Sci.119, 2236-2245. full article & pdf   

2005 

Egan, C.E., Dalton, J.E., Andrew, E. M., Smith, J.E., Gubbels, M.J, Striepen, B. and Carding, S.R. (2005) A requirement for the V1 subset of peripheral  T cells in the control of the systemic growth of Toxoplasma gondii and infection-induced pathology. J. Immonol., 175:8181-8199.

Vaishnava, S., Morrison, D., Gag, R., Murray, J., Entzeroth, R.K., Howe, D.L., and Striepen, B. (2005) Development and segregation of the plastid in the apicomplexan parasite Sarcocystis neurona. J. Cell Sci. 118: 3397-407.

Sullivan, W.J., Dixon, S.E., Li, C., Striepen, B., Queener, S.F. (2005) Cloning and characterization of inosine 5’-monophosphate dehydrogenase from Toxoplasma gondii (TgIMPDH). Antimicrob Agents Chemother. 49: 2172-9.

Howe, D.K., Gaji, R.Y., Mroz-Barret, M., Gubbels, M.J., Striepen, B., and Stamper, S. (2005) Sarocystis neurona merozoites espress a family of immunogenic surface antigens that are orthologs of the SAG/ARS surface antigens in Toxoplasma gondii. Infect. Immun. 73: 1023-33.

White, M.W., Jerome, M. E., Vaishnava, S., Guerini M., Behnke, M. and Striepen, B. (2005) Studies of a mitotic mutant yield evidence for cell cycle coordination in Toxoplasma gondii. Mol. Microbiol., 55: 1060-71.

Gubbels, M.J., Striepen, B., Shastri, N., Turkoz, M., Robey (2005) Class I MHC presentation of antigens that escape from the parasitophorous vacuole of Toxoplasma gondii. Infect. Immun., 73: 703-11.

2004

Umejiego, N.N., Li, C., Riera, T., Hedstrom, L., and Striepen, B. (2004) Cryptosporidium parvum IMP dehydrogenase: identification of functional, structural and dynamic properties that can be exploited for drug design. J. Biol. Chem., 279: 40320-40327.

Rogers, M.B., Achibald, J.M., Field, M., Li, C., Striepen, B., and Keeling, P.J. (2004) Plastid-Targeting Peptides from the Chlorarachniophyte Bigelowiella natans. J. Eukaryot. Microbiol. 51: 529-535

Gubbels, M.J., Wieffer, M., and Striepen, B. (2004) Fluorescent protein tagging in Toxoplasma gondii: identification of a novel inner membrane complex component conserved among Apicomplexa. Mol. Biochem. Parasitol. 137: 99-110.

Striepen, B. and Kissinger, J.C. (2004) Genomics meets trangenics in the search for the elusive Cryptosporidium drug target. Trends Parasitol., 20: 355-358.

Striepen, B., Pruijssers, A.J.P., Huang, Li, C., Gubbels, M.J., Umejiego, N.N., Hedstrom, L, and Kissinger, J.C (2004) Genetransfer in the evolution of parasite nucleotide biosynthesis. Proc. Natl. Acad. Sci. USA. 101: 3154-3159.

Radke, J.R., Gubbels, M.J., Jerome, M.E., Radke, J.B., Striepen, B., and White, M.W. (2004) Identification of a sporozoite-specific member of the Toxoplasma SAG superfamily via genetic complementation. Mol. Micro. 52: 93-105.

Gubbels, M.J. and Striepen, B. (2004) Studying the cell biology of apicomplexan parasites using fluorescent proteins. Microsc. Microanal. 10: 568-579.

2003

Wojczyk BS, Stwora-Wojczyk MM, Hagen FK, Striepen B., Hang HC, Bertozzi CR, Roos DS, Spitalnik SL. (2003) cDNA cloning and expression of UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase T1 from Toxoplasma gondii. Mol. Biochem. Parasitol. 131: 93-107.

Hoane, J.S., Carruthers, V.B., Striepen, B., Morrison, D.P., Entzeroth, R., and Howe, D. (2003) Analysis of the Sarcocystis neurona microneme protein SnMIC10: protein characteristics and expression during intracellular development. Int. J. Parasitol. 33:671-679.

Drozdowicz Y.M., Shaw M., Nishi M., Striepen B., Liwinski H.A., Roos D.S., Rea P.A. (2003) Isolation and characterization of TgVP1, a type I vacuolar H+-translocating pyrophosphatase from Toxoplasma gondii. The dynamics of its subcellular localization and the cellular effects of a diphosphonate inhibitor. J. Biol. Chem. 278:1075-85.

Gubbels, M.J., Li, C., and Striepen, B. (2003) A high throughput growth assay for Toxoplasma gondii using yellow fluorescent protein, Antimicrob. Agents Chemother. 47: 309-316.

2002

Neudeck, A., Stachelhaus, S., Nischik, N., Striepen, B., Reichmann, G. and Fischer, H.G. (2002) Expression variance, biochemical and immunological properties of Toxoplasma gondii dense granule protein GRA7. Microb. Infect., 4: 581-590.

Striepen, B., White, M.W., Li, C., Guerini, M.N., Malik, S.B., Logsdon, J.M., Liu, C., and Abrahamsen, M.S. (2002) Genetic complementation in apicomplexan parasites. Proc. Natl. Acad. Sci. USA, 99: 6304-6309

Hu, K., Mann, T., Striepen, B., Beckers, C.J.M., Roos, D.S. and Murray, J.M. (2002) Daughter cell assembly in the protozoan parasite Toxoplasma gondii. Mol. Biol. Cell 13:593-606 (full article & pdf)

Roos, D.S., Crawford, M.J., Donald, R.G., Fraunholz, M., Harb, O.S., He, C.Y., Kissinger, J.C., Shaw, M.K., Striepen, B. (2002) Mining the Plasmodium genome database to define organellar function: what does the apicoplast do? Philos. Trans. R. Soc. Lond. B. Biol. Sci. 357(1417):35-46.

2001

Zinecker, C.F., Striepen, B., Geyer, H., Geyer, R., Dubremetz, J.F., and Schwarz, R.T. (2001) Two Glycoforms are present in the GPI-Membrane Anchor of the Surface Antigen 1 (P30) of Toxoplasma gondii. Mol. Biochem. Parasitol. 116:127-35.

He, C.Y., B. Striepen, C.H. Pletcher, J.M. Murray and D.S. Roos. 2001. Targeting and processing of nuclear-encoded apicoplast proteins in plastid segregation mutants of Toxoplasma gondii. J. Biol. Chem., 276: 28436-28442.

Radke, J.R., Striepen, B., Guerini, M., Jerome, M.E., Roos, D.S., White, M.W. (2001) Defining the cell cycle of the tachyzoite stage of Toxoplasma gondii. Mol. Biochem. Parasitol. 115: 165-175.

Wille, U., Villegas, E.N., Striepen, B., Roos, D.S., and Hunter, C.A. (2001) IL-10 does not contribute to the pathogenesis of a virulent stain of Toxoplasma gondii. Parastit. Immunol. 23: 291-296

Striepen, B., Soldati, N., Garcia-Reguet, Dubremetz, J.F., and David Roos (2001) Targeting of soluble proteins to the rhoptries and micronemes in Toxoplasma gondii. Mol. Biochem. Parasitol. 113: 45-53 (full article & pdf)

He. C.Y, Shaw, M.K., Pletcher, C.H., Striepen, B., Tilney, L.G. and Roos, D.S. (2001) A plastid segregation defect in the protozoan parasite Toxoplasma gondii. EMBO J. 20:330-339

2000

Striepen, B., Crawford, M.J. Shaw, M.K., Tilney, L.D., Seeber, F., and Roos, D.S. (2000) The plastid of Toxoplasma gondii is divided by association with the centrosomes. J. Cell Biol., 151:1423-1434

1999 and before

Roos, D., Crawford, M.J., Donald, R.G.K., Fohl, L.M., Hager, K.M., Kissinger, J.C., Reynolds, M.G., Striepen, B., and Sullivan, W.J. (1999) Transport and trafficking: Toxoplasma as a model for Plasmodium. Novartis Fdn. Symp. 266:176-95

Roos D.S., Crawford M.J., Donald R.G., Kissinger J.C., Klimczak L.J., Striepen B. (1999) Origin, targeting, and function of the apicomplexan plastid. Curr. Opin. Microbiol. 2:2426-432 (full article & pdf)

Hager K.M., Striepen B, Tilney L.G., Roos D.S.(1999) The nuclear envelope serves as an intermediary between the ER and golgi complex in the intracellular parasiteToxoplasma gondii. J. Cell. Sci. 112:2631-2638 (full article & pdf)

Chaturvedi, S., Qi, H., Coleman, D., Rodriguez, A., Hanson, P.S., Striepen, B., Roos, D.S.,  and Joiner, K.A. (1999) Constitutive calcium independent release of Toxoplasma gondii dense granules occurs through the NSF/SNAP/SNARE/Rab machinery. J. Biol. Chem. 274:2424-2431 (full article & pdf)

Striepen, B., Dubremetz, J.F., and Schwarz, R.T.  (1999)  Glucosylation of glycosyl-phosphatidylinositols: Identification of Uridine-Diphosphate-Glucose as the direct donor for side chain modification in Toxoplasma gondii using carbohydrate analogs. Biochemistry 38:1478-1487 (full article & pdf)

Zinecker, C.F., Striepen, B., Tomavo, S., Dubremetz, J.F., and Schwarz, R.T. (1998) The dense granule antigen, GRA2 of Toxoplasma gondii is a glycoprotein containing O-linked oligosaccharides.  Mol. Biochem. Parasitol. 97(1-2):241-6

Waller, R.F., Keeling, P.J., Donald, R.G.K, Striepen, B., Handman, E., Lang-Unasch, N., Cowman, A.F., Besra, G.S., Roos, D.S., McFadden, G.I. (1998) Nuclear-encoded proteins target to the plastid in Toxoplasma gondii  and Plasmodium falciparum. Proc. Natl. Acad. Sci. USA 95: 12352-12357 (full article & pdf)

Striepen, B., He, C.Y., Matrajt, M., Soldati, D. and Roos, D.S.  (1998)  Expression, selection and organellar targeting of the green fluorescent protein in Toxoplasma gondiiMol. Biochem. Parasitol. 92: 328-338.

Roos, D.S., Sullivan, W.J., Striepen, B., Bohne, W. and Donald, R.G.K.  (1997)  Tagging genes and trapping promoters in Toxoplasma gondii by insertional mutagenesis.  Methods  13: 112-122

Striepen, B., Zinecker, C.F., Damm, J.B.L, Melgers, P.A.T., Gerwig, G.J., Koolen, M., Vliegenthart, J.F.G., Dubremetz, J.F., and Schwarz, R.T.  (1997)  Molecular structure of the "low molecular weight antigen" of Toxoplasma gondii: a glucose alpha1-4 N-acetylgalactosamine makes free glycosyl-phosphatidylinositols highly immunogenic.  J. Molec. Biol. 266:797-813. (full article & pdf)

Zinecker, C.F., Gerold, P., Azzouz, N., Striepen, B.,  Schmidt, A., Berhe, S., Kimmel, J., Keddes, M.H.,  Blackman, M.J., Schofield, L., Ougun, S., Damm, J.B.L., Melgers, P.A.T., Koolen, M., Gerwig, G. J., Vliegenthardt, J.F.G., Dubremetz, J.F., Holder, A.A., Eckert, V., Capedeville, Y., Tachado, S.D. and Schwarz, R.T.  (1997)  Glycosyl-phosphatidylinositols in protozoa:  Structure, biosynthesis and intracellular localisation. Ind. J. Biochem. Biophys. 34:105-109.

Gerold, P.*, Striepen, B.*, Reitter, B., Geyer, H., Geyer, R., Reinwald, E., Risse, H.J., and Schwarz, R.T.  (1996)  Glycosyl-phosphatidylinositols of Trypanosoma congolense: two common precursors but a new protein-anchor. J. Molec. Biol. 261:181-94.

Azzouz, N., Striepen, B., Gerold, P., Capdeville, Y., and Schwarz, R.T.  (1995)  Glycosylinositol-phosphoceramide in the free-living protozoan Paramecium primaurelia:  Modification of core glycans by mannosyl phosphate. EMBO J. 14:4422-1433.

Striepen, B., Tomavo, S., Dubremetz, J.F., and Schwarz, R.T.  (1992)  Identification and characterisation of glycosyl-inositolphospholipids in Toxoplasma gondiiBiochem. Soc. Trans. 20:296S.
 

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